Switzerland

Back to Search

International Partner Search

Innovation & Technology Offer

Italian technology of method and apparatus for acquisition of magnetic resonance data offered for license agreement

Country of Origin: Italy
Reference Number: TOIT20170821002
Publication Date: 29 August 2017

Summary

A team of Italian researchers operating in the field of medical imaging is looking for industrial partners, manufacturers of magnetic resonance equipment, for license agreement. Technology offer relates to an innovative, high field Magnetic Resonance spectroscopy system and method that provides a quick sequential detection of the MR signal coming from two different nuclei, using all resonance modes of the TEM coil, which allows selecting the most fitting region of interest.

Description

The inventors of this innovative technology are a research group who focused their activity research in applied physics in the field of medical imaging and tomography. 
Magnetic resonance (MR) is a matter survey technique based on the measurement of the spin precession of protons or other cores provided with magnetic moment when in the presence of a static magnetic field and disturbed by an oscillating external magnetic field. The standard MR clinical instrumentation currently operates at magnetic field values of 1.5 Tesla and it is estimated that more than 10.000 MR scanners are installed at hospitals and public and private research centres worldwide.
In the prior art of magnetic resonance acquisition techniques and apparatuses, the measurements related to a same sample are carried out strictly configuring in the construction and setup step the radiofrequency coil to be used in transmission and/or reception, so that it has a resonant mode that among those available is deemed by the man skilled in the art the most suitable one for magnetic resonance observations at a specific Larmor frequency. Magnetic resonance measurements are therefore strongly influenced by the spatial distribution of the sensitivity profile corresponding to the resonant mode selected by the man skilled in the art.
The team of Italian researchers has developed an innovative, high field (3-12 Tesla), MR spectroscopy system and method that provides a quick sequential detection of the MR signal coming from two different nuclei, using all resonance modes of the TEM (Transverse Electromagnetic) coil, which allows selecting the most fitting region of interest.
The field of application of this invention is for diagnostic purposes in the so-called magnetic resonance imaging which is widely used in clinical and research applications with cells, tissues, organs and animal model.
The innovation is protected by a patent granted in United States.
The university is looking for industrial partners with focus on manufacturers of magnetic resonance equipment, for license agreement.
The stage of development of the invention is a working prototype.

Advantages and Innovations

Larger Field of View (FOV) and better control of it, compared to the state of the art.
Better spatial overlap of the images reconstructed from the two nuclei signals.
Higher accuracy, obtained with repeated acquisitions using more than one resonance mode to detect the signal from each nucleus.
Ultrafast detection mode, thanks to a new hardware that allows a fast and sequential selection of the coil resonant modes.
Easiness and effectiveness of usage for end-users.

Expertise sought

The present invention relates to a magnetic resonance method and apparatus with sequential selection of resonant modes. 
The method for acquiring magnetic resonance data from a sample to be analysed, comprising:
- a step of arranging the sample in the proximity of at least one radiofrequency coil;
- a first step of synthesizing through a control unit a first control signal;
- a first step of acquiring a first magnetic resonance signal from the sample;
- a second step of synthesizing through the control unit a second control signal;
- a second step of acquiring a second magnetic resonance signal from the sample.
The apparatus is a dual tuned surface coil capable to receive, at the same time, the MRI (Magnetic Resonance Imaging) signal of two different NMR (Nuclear Magnetic Resonance) active nuclei present in the sample to analyse. The coil is a TEM antenna suitable for high field MRI scanners and human imaging. As standard surface coils the invention has a very high sensitivity close to the coil itself.

Stage Of Development

Prototype available for demonstration

Requested partner

Type of partner sought: SME, MNE.
Specific area of activity of the partner: producers of magnetic resonance equipment
Task to be performed by the partner sought: acquiring a license.

Contact Profile Owner